Reichenbach worked in an era when philosophers were hopeful about the unity of science, and particularly about unity of method. He looked for universal tests of causal connectedness that could be applied across disciplines and independently of specific modeling assumptions. The hunt for quantum causes reminds us that his hopes were too optimistic. The mark method is not even a starter in testing for causal links between outcomes in E.P.R., because our background hypotheses about these links are too thin to (...) supply the kind of information we need to put the method into play. When we turn to conventional statistical methods, we have seen that one test proposed — robustness of the conditional probabilities — can be conclusive only when we know that there are no other causal factors at work. In the particular case of E.P.R., it has often been assumed that this antecedent question can be settled by applying Reichenbach's conjunctive fork condition. But that application is in no way free of further modeling assumptions. Cartwright (1989) has shown that the conjunctive fork is only a necessary condition on a common cause under very limiting restrictions (restrictions that take one far from the case of maximal commonality); and she has argued that these special conditions are not satisfied in E.P.R.Finally, even given the assumption that there are no other causes at work, the significance of robustness for E.P.R. is unclear. We need a model which tells us how one outcome would influence the other; without that, there is no way of interpreting the results of the robustness test so that it is decisive. In each of the approaches we discussed, Reichenbach provided the crucial guiding ideas that underlay our construction of a causality test; but the articulation of a specific criterion depends on the other details of the model. What is a criterion for a specific kind of link in one model need not be in another. We have illustrated with robustness and E.P.R., but we take the point to be perfectly general: there are no tests of causality outside of models which already have significant causal structure built in. (shrink)

The activities of the life sciences are essential to provide solutions for the future, for both individuals and society. Society has demanded growing accountability from the scientific community as implications of life science research rise in influence and there are concerns about the credibility, integrity and motives of science. While the scientific community has responded to concerns about its integrity in part by initiating training in research integrity and the responsible conduct of research, this approach is minimal. The scientific community (...) justifies itself by appealing to the ethos of science, claiming academic freedom, self-direction, and self-regulation, but no comprehensive codification of this foundational ethos has been forthcoming. A review of the professional norms of science and a prototype code of ethics for the life sciences provide a framework to spur discussions within the scientific community to define scientific professionalism. A formalization of implicit principles can provide guidance for recognizing divergence from the norms, place these norms within a context that would enhance education of trainees, and provide a framework for discussing externally and internally applied pressures that are influencing the practice of science. The prototype code articulates the goal for life sciences research and the responsibilities associated with the freedom of exploration, the principles for the practice of science, and the virtues of the scientists themselves. The time is ripe for scientific communities to reinvigorate professionalism and define the basis of their social contract. Codifying the basis of the social contract between science and society will sustain public trust in the scientific enterprise. (shrink)

Historian James H. Jones published the first edition of Bad Blood, the definitive history of the Tuskegee Syphilis Experiment, in 1981. Its clear-eyed examination of that research and its implications remains a bioethics classic, and the 30-year anniversary of its publication served as the impetus for the reexamination of research ethics that this symposium presents. Recent revelations about the United States Public Health Service study that infected mental patients and prisoners in Guatemala with syphilis in the late 1940s in (...) order to determine the efficacy of treatment represent only one of the many attestations to the persistence of ongoing, critical, and underaddressed issues in research ethics that Bad Blood first explored. Those issues include, but are not limited to: the complex and contested matters of the value of a given research question, the validity of the clinical trial designed to address it, and the priorities of science. (shrink)

The principal task of the book series Poznan Studies in the Philosophy of the Sciences and the Humanities is to promote those developments in philosophy that respect the tradition of great philosophical ideas, on the one hand, and the manner of philosophical thinking introduced by analytical philosophy, on the other. The aim is to contribute to practicing philosophy as deep as Marxism and as caring about justification as positivism.

Scientific endeavor is the pursuit of knowledge with the aim of advancing the welfare of all human beings. This endeavor is built on the ideology of science; thus, society relies on the integrity of the practice of science and of scientists themselves. The responsible conduct of research is the essence of good science; however, many of the pedagogical approaches used to instill integrity in science accentuate the negative rather than exemplify ideal professionalism. This paper makes an argument for the inculcation (...) of the appropriate conduct of research via a positive approach. We address the acclimation to the culture of science that supersedes diverse cultural backgrounds of students. We suggest techniques for the implementation of positive strategies and reinforce the benefit of approaching the teaching of ethical behavior as a competitive advantage. We highlight ways in which this approach can empower the individual scientist and the scientific community as a whole. Transmission of the culture of scientific professionalism formalizes the aims of an ideal scientific professional and encourages assimilation and identification as a member of the scientific profession. We purport that instilling scientific professionalism will spur responsible conduct of research. (shrink)

Book reviewed in this article: Practical Medical Ethics. By Alastair Campbell, Grant Gillett, and Gareth Jones. If I Were a Rich Man Could I Buy a Pancreas? and Other Essays on the Ethics of Health Care. By Arthur L. Caplan. Bloomington Ethics on Call: A Medical Ethicist Shows How to Take Charge of Life and Death Choices in Today's Health Care System. By Nancy Dubler and David Nimmons.

The volume is a collection of essays devoted to the analysis of scientific change and stability. It explores the balance and tension that exist between commensurability and continuity on the one hand, and incommensurability and discontinuity on the other. Moreover, it discusses some central epistemological consequences regarding the nature of scientific progress, rationality and realism. In relation to these topics, it investigates a number of new avenues, and revisits some familiar issues, with a focus on the history and philosophy of (...) physics, and an emphasis on developments in cognitive sciences as well as on the claims of “new experimentalists”. The book constitutes fully revised versions of papers which were originally presented at the international colloquium held at the University of Nancy, France, in June 2004. (shrink)

_341_ _Objectives: _In patients with multivessel disease both the detection of the culprit lesion and the exact allocation are important preconditions for sufficient treatment and improved outcome. In a vessel based approach the combination of quantitative coronary angiography and fractional flow reserve measured by a pressure wire should be advantageous compared to myocardial SPECT, as morphological and functional information is delivered simultaneously. Therefore our aim was to evaluate MS in the detection and allocation of hemodynamically significant stenoses obtained by the (...) combined gold standard QCA plus FFR in patients with multivessel disease. _Methods: _FFR and QCA of 95 vessels in 80 patients have been evaluated. Hemodynamically significant target lesions were defined as intermediate stenoses between 50 and 75% with an FFR. (shrink)

Nanomedicine is yielding new and improved treatments and diagnostics for a range of diseases and disorders. Nanomedicine applications incorporate materials and components with nanoscale dimensions where novel physiochemical properties emerge as a result of size-dependent phenomena and high surface-to-mass ratio. Nanotherapeutics and in vivo nanodiagnostics are a subset of nanomedicine products that enter the human body. These include drugs, biological products, implantable medical devices, and combination products that are designed to function in the body in ways unachievable at larger scales. (...) Nanotherapeutics andin vivonanodiagnostics incorporate materials that are engineered at the nanoscale to express novel properties that are medicinally useful. These nanomedicine applications can also contain nanomaterials that are biologically active, producing interactions that depend on biological triggers. Examples include nanoscale formulations of insoluble drugs to improve bioavailability and pharmacokinetics, drugs encapsulated in hollow nanoparticles with the ability to target and cross cellular and tissue membranes and to release their payload at a specific time or location, imaging agents that demonstrate novel optical properties to aid in locating micrometastases, and antimicrobial and drug-eluting components or coatings of implantable medical devices such as stents. (shrink)

This paper is significant in its exploration of the experiences of children designated as ‘lower-attaining’ in British primary schooling. It is underpinned by Nancy Fraser’s conceptualisation of a global shift from government via nation-state welfare structures to governance through supra-national financialised neoliberalism. Within this context, we take the innovative path of investigating how ‘lower-attaining’ children explain perseverance with hard work at school within neoliberalism’s ‘cruel and cynical fiction’ of social mobility. Our extended interviews with 23 ‘lower-attaining’ children over two (...) years provide findings which indicate – with a startling vividness – that these particular children experienced loneliness at school and blamed themselves for being inadequate and inferior. Fear appeared to be an essential component of their schooling system and sometimes elicited from them anger as well as humiliation. In particular, these children feared being assessed and sorted according to attainment. We propose that these factors often led the ‘lower-attaining’ children to experience schooling as at least uncomfortable. And yet they came to accept as fact the fiction that they were inadequate; and to perceive that perseverance in conforming to schooling’s rules was their only chance of not slipping out of the race altogether. (shrink)

Long-running horror series are reputed to yield diminishing returns (both in terms of profit and quality). At first glance, the A Nightmare on Elm Street series appears to fit that established pattern. For instance, lead antagonist Freddy supposedly ‘deteriorates’ from sinister, backlit child molester to comic-book ‘Las Vegas lounge’ stand-up act by the end of the 1980s (Schoell and Spencer 1992, 116). However, interviews from the period indicate that comedy was a central component from the outset of the series; it (...) is not, as has been often suggested, that the series’ horror was diluted by the introduction of humour in later sequels. Such misremembrances are entrenched by the writers’, directors’ and actors’ retrospective reflections on Elm Street, which colour how the series is understood more broadly. This chapter will focus on one of the most common misremembrances embedded into Elm Street’s lore; that the series began with hard rules about the relationship between dream and reality, which became looser (to the point of incoherence) as the series progressed. As close textual analysis and examination of archival interviews will demonstrate, the series’ “rules” were never as clearly established as creator Wes Craven intended. Moreover, rather than complaining that the continuing story did not hold together—indeed, Craven dismissed parts 2-6 of the series on these grounds—I argue that the series ought to be taken on its own terms. The individual films may vary in aesthetic and quality for various industrial reasons, but they are nevertheless chapters in a continuing narrative, and ought to be understood as such. Given that the diegesis is based on shared experiences—secrets held by Springwood’s parents, nightmares and abilities shared by the teens—it is reductive to understand the Elm Street films as anything other than an imbricated whole. As such, this chapter will demonstrate that the series’ narrative is best understood as a recurring nightmare. Its logic is dreamlike, being constituted by events, characters and motifs that are echoed across the series. Thus, this chapter contends that to dismiss the Elm Street sequels as a product of diminishing returns is to overlook the series’ narrative richness. More broadly, this chapter makes a case for understanding sequels as valuable parts of a whole, rather than dismissing them as inferior copies of the original. (shrink)

"... Fraser and Bartky have brought the encounter between U.S. and French feminism to a new level of seriousness." —Ethics In the last decade, elements of French feminist discourse have permeated and transformed the larger feminist culture in the United States. This volume is the first sustained attempt to revalue French feminism and answer the question: What has been gained and what has been lost as a result of this intercultural encounter? Interviews with Simone de Beauvoir open the book; essays (...) by French feminists Sarah Kofman and Luce Irigaray follow; the North American contributors are Judith Butler, Nancy Fraser, Diana J. Fuss, Nancy J. Holland, Eleanor H. Kuykendall, Dorothy Leland, Diana T. Meyers, Andrea Nye, and Margaret A. Simons. (shrink)

This experiment examined the effects of three elements comprising Jones' (1991) moral intensity construct, (social consensus, personal proximity, and magnitude of consequences) in a cross-cultural comparison of ethical decision making within a human resource management (HRM) context. Results indicated social consensus had the most potent effect on judgments of moral concern and judgments of immorality. An analysis of American, Eastern European, and Indonesian responses also indicted socio-cultural differences were moderated by the type of HRM ethical issue. In addition, individual (...) differences in personal ethical ideology (relativism and idealism) varied reliably with moral judgments after controlling for issue characteristics and socio-cultural background. (shrink)

Is the universe really governed by a small set of unifying fundamental laws, as many thinkers have claimed since ancient times? Philosophers who call themselves naturalists believe that the way to settle such questions is to look carefully at what empirical science tells us. In this book, Margaret Morrison argues that if we really do this, we find that science currently does not give us any reason to believe the common picture of the world in which everything can be reduced (...) to a vanishingly small set of entities and forces. Like Nancy Cartwright and John Dupree, Morrison believes that science reveals a world of numerous different sorts of entities and processes, described by different sorts of explanation. Trying to come up with unified descriptions of phenomena does play an important role in science, says Morrison, but there are different types of unification. The sort in which one set of entities can be reductively identified with another occurs rarely. What we find more often are various ways of subsuming different phenomena under similar mathematical formalisms. An urge to unify, in different guises, is an important research motivator, Morrison argues, but it is not the sort of monolithic engine of science that many make it out to be. (shrink)

Admissions to upper-tier universities have become increasingly competitive. The erosion of gains made during the Civil Rights Era is evidenced by recent legal actions at the University of Michigan. In this paper I argue that affirmative action programs remain a necessary means for achieving social justice. Further, I argue that more than mere affirmative action, what is also required is Nancy Fraser’s “Transformative Action.” To reach these conclusions, the paper is divided into three parts: (1) The continued assault on (...) Affirmative Action; (2) the SAT and race; and (3) transformative action. (shrink)

This volume focuses on the relational aspect of Jean-Luc Nancy's thinking. As Nancy himself showed, thinking might be a solitary activity but it is never singular in its dimension. Building on or breaking away from other thoughts, especially those by thinkers who had come before, thinking is always plural, relational. This "singular plural" dimension of thought in Nancy's philosophical writings demands explication. In this book, some of today's leading scholars in the theoretical humanities shed light on how (...) Nancy's thought both shares with and departs from Descartes, Hegel, Marx, Heidegger, Weil, Lacan, Merleau-Ponty, and Lyotard, elucidating "the sharing of voices," in Nancy's phrase, between Nancy and these thinkers. Contributors: Georges Van Den Abbeele, Emily Apter, Rodolphe Gasché, Werner Hamacher, Eleanor Kaufman, Marie-Eve Morin, Timothy Murray, Jean-Luc Nancy, and John H. Smith. (shrink)

Targeting injustices that cut across borders, they are making the scale of justice an object of explicit struggle.Inspired by these efforts, Nancy Fraser asks: ...

Interpreting crises and transformative processes as complex and rhythmic phenomena A webinar with Prof. Michel Alhadeff-Jones - Sciences de l'éducation et de la formation.

In their article, Pavarani and colleagues offer a vision of evolutionary bioethics that focuses on innovation and empirical research as a means to enrich the field of bioethics. Empirical bi...

What does it mean to say that this person at this time is 'the same' as that person at an earlier time? If the brain is damaged or the memory lost, how far does a person's identity continue? In this book two eminent philosophers develop very different approaches to the problem.

This paper has already been published in the European Journal for Research on the Education and Learning of Adults, Vol. 12, No. 3 : Learning in times of crisis.: The aim of this paper is to problematize and enrich the use of the concept of crisis in adult education to theorize further its contribution to the study of transformative processes. This paper discusses first the implications inherent in the adoption of event-based and processual approaches to crises. It seeks - Sciences (...) de l'éducation et de la formation – Nouvel article. (shrink)

This chapter contains sections titled: Introduction: Complexity versus Complexities Etymological Roots Contemporary Genesis First Generation Second Generation Third Generation Keeping Complexity Complex Towards a New Form of Critique? Notes References.

Ageism within the context of care has attracted increasing attention in recent years. Similarly, autonomy has developed into a prominent concept within health care law and ethics. This paper explores the way that ageism, understood as a set of negative attitudes about old age or older people, may impact on an older person’s ability to make maximally autonomous decisions within health care. In particular, by appealing to feminist constructions of autonomy as relational, I will argue that the key to establishing (...) this link is the concept of self-relations such as self-trust, self-worth and self-esteem. This paper aims to demonstrate how these may be impacted by the internalisation of negative attitudes associated with old age and care. In light of this, any legal or policy response must be sensitive to and flexible enough to deal with the way in which ageism impacts autonomy. (shrink)

Nancy Cartwright; XII*—Fundamentalism vs. the Patchwork of Laws, Proceedings of the Aristotelian Society, Volume 94, Issue 1, 1 June 1994, Pages 279–292, https.

Against the backdrop of the recent emergence of disturbing currents of populism in several countries, including the United States, this article argues for a conception of hope as a democratic civic virtue. In section 1, it offers a general overview of hope and sketches an initial conception of hope as a democratic civic virtue. In section 2, the stage is set for further theorizing of this conception in the present American context. Drawing on the work of Ghassan Hage, the article (...) makes the point that the United States is in the process of becoming a nation of worriers in part because of the failure of the government to distribute social hope. Section 3 fleshes out what hope as a democratic civic virtue could look like in the United States today. Section 4 concludes with brief comments about theorizing civic hope in the context of a modified pragmatism. (shrink)

In Gender, Class, and Freedom in Modern Political Theory, Nancy Hirschmann demonstrates not merely that modern theories of freedom are susceptible to gender and class analysis but that they must be analyzed in terms of gender and class in order to be understood at all. Through rigorous close readings of major and minor works of Hobbes, Locke, Rousseau, Kant, and Mill, Hirschmann establishes and examines the gender and class foundations of the modern understanding of freedom. Building on a social (...) constructivist model of freedom that she developed in her award-winning book The Subject of Liberty: Toward a Feminist Theory of Freedom, she makes in her new book another original and important contribution to political and feminist theory. Despite the prominence of "state of nature" ideas in modern political theory, Hirschmann argues, theories of freedom actually advance a social constructivist understanding of humanity. By rereading "human nature" in light of this insight, Hirschmann uncovers theories of freedom that are both more historically accurate and more relevant to contemporary politics. Pigeonholing canonical theorists as proponents of either "positive" or "negative" liberty is historically inaccurate, she demonstrates, because theorists deploy both conceptions of freedom simultaneously throughout their work. (shrink)